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Can Suboxone Cause an Overdose?

Although most people who take Suboxone as directed by their physician are not likely to overdose on this long-acting partial opioid agonist, mixing the drug with other substances – especially other opioids, alcohol, or benzodiazepines – increases its bioavailability to the opioid receptors. This amplifies intoxication as well as the risk of overdose.

Signs of an overdose on Suboxone include:

  • Slowed heart rate
  • Tension, anxiety, or irritability
  • Loss of physical coordination
  • Sleepiness
  • Trouble concentrating
  • Nausea
  • Seizures
  • Stomach pain
  • Depressed breathing

If a person is overdosing on any opioid or Suboxone, call 911 immediately. The individual needs emergency medical treatment.